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 A Paper I READ

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Dr.J.Prakasa Rao



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PostSubject: A Paper I READ   Tue Jan 30, 2007 1:12 pm

IS OBESITY A MICROBIAL DISEASE?
No! But a link seems to exist. Bacterial flora isolated from lean and obese subjects, men or mice, seem to be different. Those from the obese are capable of breaking complex carbohydrates into simple absorbable sugars. So an obese person obtains more calories than a lean person from the same diet. When such bacteria are placed in the gut of lean mice, the animals seem to gain weight! The gain may be small but significant and over the time period of years may contribute to obesity. If you wish to know more about it, read NATURE444:1009, Dec 2006.
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christofer thomas



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PostSubject: Re: A Paper I READ   Sun Feb 04, 2007 1:23 am

i had read it sir,i have a copy also......
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mohd bayazuddin



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PostSubject: sir.....is it   Sun Feb 11, 2007 2:49 am

so Sir this obese microbe can be used to gain weight in lean persons?if it is then after a period of time won't it cause metabolic problems........... Question [i]
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Dr.J.Prakasa Rao



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PostSubject: Re: A Paper I READ   Mon Feb 12, 2007 10:37 pm

So far these expts have been done on mice only.
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Dr.J.Prakasa Rao



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PostSubject: Re: A Paper I READ   Sat Feb 17, 2007 9:00 pm

A Paper I READ (2)
how to induce Depression in mice: Simple! Subject them to Stress. But how do you stress them? By exposing them to the following for 5weeks.
A) Water deprivation for 16hrs at a stretch once a week
B) Tilt the cage to 45 degrees for 3hrs twice in a week.
C) Keep for 17hrs in a soiled (not cleaned) cage once a week.
D) Expose to noise stress for 3hrs twice a week.
E) Expose to stroboscopic illumination for 10 mins thrice in a week( Strobe lights are used on stage in rock shows!)
HOW DO WE KNOW THEY ARE DEPRESSED AT THE END OF THIS?
Conduct Sucrose Preference Test: Keep two drinking bottles containing water and 2% sucrose solution respectively. After 4hrs of exposure of a mouse to these, find out the toal fluid intake and the%of sucrose solution in this total.
STRESSED ANIMALS DRINK LESS SUCROSE WHEN COMPARED TO NORMALS. If you want to read more, refer to PNAS 103:45:16876-16881,2006. 'Depression induces bone loss'
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anandbhaskar



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PostSubject: Re: A Paper I READ   Sat Feb 17, 2007 9:10 pm

Sir, that was interesting.
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mohd bayazuddin



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PostSubject: Re: A Paper I READ   Tue Feb 20, 2007 12:18 am

sir,thatz really interesting to know.......
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Doniya Joson



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PostSubject: Re: A Paper I READ   Tue Feb 27, 2007 5:43 pm

Sir its really interesting.
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dipanwita



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PostSubject: Re: A Paper I READ   Fri Mar 02, 2007 3:09 am

interesting article sir...
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Dr.J.Prakasa Rao



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PostSubject: Re: A Paper I READ   Sat Mar 03, 2007 8:59 pm

A Paper I Read(3)
BICEPS BENEFITS: If you excercise your left biceps, will it benefit your right biceps? A recent analysis of papers published over a century( J.Applied Physiology 101:1514-1522, 2006) suggests that it does! Unilateral training increases the strength of the contralateral resting biceps too. The benefit is about 50% compared to the active muscle. The increased strength is restricted to only biceps not to other muscles of the contralateral side. This excludes the possibility of a chemical factor released by the active muscle and circulated to the other side, being responsible for the benefit. Certainly neural factors must be considered. There is evidence (imaging technics and trans-cranial magnetic stimulation) to show that connecting links between the two sides at cortical, subcortical and spinal level are strengthened during unilateral excercise training. However these do not completely account for the observed changes. Also when right limb is excercised the benefit to the left is better than when it is performed in the reverse! This indicates that left hemisphere(controlling the right limb) can develop better ipsilateral connections when the right limb is trained.
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anandbhaskar



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PostSubject: Re: A Paper I READ   Sat Mar 03, 2007 9:33 pm

Interesting, but I didn't understand the following statement
Quote :
Also when right limb is excercised the benefit to the left is better than when it is performed in the reverse!
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Dr.J.Prakasa Rao



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PostSubject: Re: A Paper I READ   Sun Mar 04, 2007 8:58 pm

Dear Anand,
When the left biceps is exercised the benefit to the right is comparatively less. This is because the connections the right hemisphere develops with the ipsilateral limb during training are less comparatively. JPRao.
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anandbhaskar



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PostSubject: Re: A Paper I READ   Sun Mar 04, 2007 10:44 pm

Now I understood. Thank you sir.
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Snehunsu Adhikari



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PostSubject: Re: A Paper I READ   Wed Mar 07, 2007 11:21 pm

SIR, ITS REALLY INTERESTING...BUT SIR IF THE STRESS IS IN THE FORM OF HUNGER THEN ALSO THE STRESSED RATS WILL TAKE LESS SUCROSE...
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Dr.J.Prakasa Rao



Number of posts : 14
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PostSubject: Re: A Paper I READ   Sun Mar 18, 2007 7:49 pm

A Paper I Read(4)
AN INFLAMMATORY REFLEX!
Every reflex operates through a reflex arc.This has also one.
Stimulus: Inflammation
Receptors: Bare nerve endings(probably)
Afferents: Travel in Vagus
Efferents: through Vagus again
Centre: Vagal nucleus
Effect: Reduction in inflammation
How: By inhibiting the release of inflammatory mediators
Benefit: Unchecked inflammation by itself can damage the tissue and produce diseases like inflammatory bowel disease and arthritis.This reflex may help in prevention of such diseases.
Proof: Administration of interleukin 1 causes fever in animals. But sub-diaphragmatic Vagotomy prevents this response.
Experimental pancreatitis can be induced in mice by intraperitoneal injection of caerulein. Prior cervical vagatomy or blockade of nicotinic receptors can lead to worsening of pancreatitis( assessed by histology, oedema,enzyme levels). However administration of GTS-21 a stimulant of alpha 7 subunit of nicotinic receptor confers benefit.
Is it too good to beleive! Check out J.Clin. Investigation 117:289-296,(2007).
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Dr.J.Prakasa Rao



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PostSubject: Re: A Paper I READ   Mon Mar 19, 2007 8:59 pm

A Paper I Read(5)
LENTECTOMY
Removal of lens inhumans is not followed by regeneration. However, Newts, salamander like aquatic animals (not found in India) are capable of regenerating the lens after damage. When a lens is pricked with a needle through the cornea, it undergoes vacuolation and destruction. Subsequently it is engulfed by dendritic cells. But surprisingly a new lens seems to form, strangely from the iris. The pigment epithelial cells of iris seem to trans-differentiate into lens epithelium! What stimulates the iris to do so? Fibroblast growth factors may be involved. Can this happen in humans? No, not right now! If you are interested in tissue regeneration or tissue engineering, read the symposium issue of Journal of Anatomy 209 October 2006
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bittoo kumar surlya



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PostSubject: Re: A Paper I READ   Tue Mar 20, 2007 2:08 am

Dr.J.Prakasa Rao wrote:
IS OBESITY A MICROBIAL DISEASE?
No! But a link seems to exist. Bacterial flora isolated from lean and obese subjects, men or mice, seem to be different. Those from the obese are capable of breaking complex carbohydrates into simple absorbable sugars. So an obese person obtains more calories than a lean person from the same diet. When such bacteria are placed in the gut of lean mice, the animals seem to gain weight! The gain may be small but significant and over the time period of years may contribute to obesity. If you wish to know more about it, read NATURE444:1009, Dec 2006.
.........thanks
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bittoo kumar surlya



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PostSubject: Re: A Paper I READ   Tue Mar 20, 2007 2:11 am

dear Sir I read your Artical is real v. intersted. thanks
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Pragha



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PostSubject: Re: A Paper I READ   Tue Mar 20, 2007 6:57 pm

Regeneration of Body Parts:

Some species in the animal kingdom even have the ability to regenerate their cut off limbs.

So, if the exact mechanism of tissue regeneration is unravelled, it would the greatest boon for the human kind. Especially for those who loose their limbs in road traffic accidents.
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Snehunsu Adhikari



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PostSubject: Re: A Paper I READ   Tue Mar 20, 2007 10:27 pm

Pragha wrote:
Regeneration of Body Parts:

Some species in the animal kingdom even have the ability to regenerate their cut off limbs.

So, if the exact mechanism of tissue regeneration is unravelled, it would the greatest boon for the human kind. Especially for those who loose their limbs in road traffic accidents.
.........dear sir,i read your artical it is real v.good.but dear sir the concept of
regeneration or produce AS cells in the human being some extend is possible.but not impossible......this is work will be magic in human kind.
.....................thanks
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Snehunsu Adhikari



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PostSubject: Re: A Paper I READ   Fri Mar 30, 2007 5:11 pm

Its very nice sir...now I got my answer...
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Snehunsu Adhikari



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PostSubject: Re: A Paper I READ   Fri Mar 30, 2007 5:29 pm

Dear sir, its unbelivable thought ...one of our biochem faculty of KMC,Manipal,is doing the same resurch on amputed leg of frog in her PDF,in USA..
Once she came to manipal and gave one guest lecture what they look for..its really very interesting sir..
thank you...[/b]
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Doniya Joson



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PostSubject: Re: A Paper I READ   Sun Apr 08, 2007 1:54 am

Yes ofcourse sir. Its good to know and believe.......
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Doniya Joson



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PostSubject: Re: A Paper I READ   Sun Apr 08, 2007 1:55 am

Yes ofcourse sir. Its good to know and believe.......
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Dr.J.Prakasa Rao



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PostSubject: Re: A Paper I READ   Thu Apr 19, 2007 9:38 pm

A paper I read (6)
MOTHER'S STRESS CHILD'S DISTRESS
Does stress in pregnant women lead to abnormalities in the off-spring? Maternal nutritional status can certainly affect the foetal health. But the link with maternal stress is yet to be clearly established. Any stress in rats leads to an increase in circulating levels of corticosterone. Comparable elevation in pregnant rats, by injection of corticosterone seems to affect the health of their new-born which showed (1) a decrease in the number of nephrons in the kidneys (2) a rise in blood pressure and (3) an up regulation of angiotensin receptors. Certainly the development of renal system is affected by just two injections of the steroid hormone at a critical period of pregnancy.The authors (Singh et al J.Physiology 579:503-513, 2007) found no changes in body weight or growth of the foetus under these conditions. They feel that their findings have major implications for normal birth weight babies born to women stressed during early stage of pregnancy.
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