What mediates tubuloglomerular feedback? Current evidence support the role of ATP and adenosine as potential mediators. A new concept of ATP-adenosine axis in the juxtaglomerular apparatus explains the importance of both these molecules for tubuloglomerular feedback.

To know more visit: http://www.blackwell-synergy.com/doi/full/10.1111/j.1748-1716.2006.01610.x

Very interesting review!

Where is macula densa located in the kidney? Is it located in the distal tubule or in the thick ascending limb?

Actually it is at the junction but many consider it as a part of TALH. JPRao